Yeast bioluminescence assays for endocrine disrupters Back to list of tests

Yeast bioluminescence assays for endocrine disrupters

Description:

Assessment of chemical (or sample) potencies to activate estrogen (ER) or androgen (AR)receptor-dependent luciferase in transgenic yeast strain (general mechanism of endocrine disruption)

Reference:
Leskinen P. et al. (2005) Chemosphere 61:259–266.

Categorization of the assay/approach:

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Application domain:

Categorization according to "exposure duration/effect":

Categorization according to combination of type of effect, endpoint measured and/or method used:

Categorization according to what "R" from the "3R" concept is this assay an alternative: