Stepdown approach Back to list of tests

Stepdown approach

Description:

Test results (EC50) of lower organisms (algae, and daphnids) are evaluated, in the absence of fish LC50 data to derive PNECwater values.

Reference:
Hutchinson T., H. et al. (2003) Environ.Toxicol. Chem. 22(12), 3031-3036

Categorization of the assay/approach:

Status of the assay:

Application domain:

Categorization according to "exposure duration/effect":

Categorization according to combination of type of effect, endpoint measured and/or method used:

Categorization according to what "R" from the "3R" concept is this assay an alternative:

Details:

Another reference: OECD (2010b) . Number 126. Short Guidance on the Threshold approach for Acute Fish Toxicity. ENV/JM/TG(2010)/7