Experimental design - fish bioconcentration Back to list of tests

Experimental design - fish bioconcentration


Improvement of the bioconcentration test experimental design - reduction in number of animals & number of concentrations used. Statistical power remains at similar level as in the standard assay.

Springer T.A. et al. (2008) Environ Toxicol Chem. 27(11), 2271-2280 / De Wolf W. et al. (2007) Integr. Environ. Assess. Manag. 3 (1), 3-17.

Categorization of the assay/approach:

Status of the assay:

Application domain:

Categorization according to "exposure duration/effect":

Categorization according to combination of type of effect, endpoint measured and/or method used:

Categorization according to what "R" from the "3R" concept is this assay an alternative: