ZFET cholinesterases carboxylesterases inhibition Back to list of tests

ZFET cholinesterases carboxylesterases inhibition

Description:

Suborganismic effects were examined analysing the enzyme inhibition of cholinesterases and carboxylesterases

Reference:
K├╝ster and Altenburger, Chemosphere. 2007 Jun;68(4):751-60. Epub 2007 Feb 9.

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Details:

Suborganismic effects were examined analysing the enzyme inhibition of cholinesterases and carboxylesterases, the enzyme inhibition analysis of whole homogenates of exposed embryos may be advantageous for toxicant screening (biomarker of exposure) and might be used to bridge the gap of sensitivity of the (48h old) zebrafish embryos to adult fish when exposed to anti-cholinesterase substances (biomarker of prospective effect).