Bird embryo lethality assay Back to list of tests

Bird embryo lethality assay

Description:

Effets on pupping success in chicken embryos in ovo

Reference:
Crump et al., Toxicol Sci. 2010 Jun;115(2):492-500

Categorization of the assay/approach:

Status of the assay:

Application domain:

Categorization according to "exposure duration/effect":

Categorization according to combination of type of effect, endpoint measured and/or method used:

Categorization according to what "R" from the "3R" concept is this assay an alternative:

Details:

The substances were injected into the air cell of the chicken eggs to determine effects on embryo pipping success. LD50 values are determined based on rate of hatching the birds