Fish primary cell biotransformation Back to list of tests

Fish primary cell biotransformation

Description:

Biotransformation assay in primary fish hepatocytes

Reference:
Cravedi JP et al., Xenobiotica. 1999 May;29(5):499-509.

Categorization of the assay/approach:

Status of the assay:

Application domain:

Categorization according to "exposure duration/effect":

Categorization according to combination of type of effect, endpoint measured and/or method used:

Categorization according to what "R" from the "3R" concept is this assay an alternative:

Details:

Biotransformation assay in primary rainbow trout (Oncorhynchus mykiss) hepatocytes (Cravedi JP et al., Xenobiotica. 1999 May;29(5):499-509., Cravedi JP et al., Aquat Toxicol. 2001 Aug;53(3-4):159-72.)

Transport of D-glucose into rainbow trout (Oncorhynchus mykiss) and river lamprey (Lampetra fluviatilis) hepatocytes was studied using tracer methods (Mannerström M et al., Comp Biochem Physiol A Mol Integr Physiol. 2003 Nov;136(3):779-90.)